In each country there is a National coordinator who is officially appointed by the Central Project Commission (CPC). Some countries may have regional coordinators representing more than one nations.
National coordinators are responsible for initiating and monitoring the study in their regions and thus establishing a regional network of Reporting physicians. To this purpose, they promote the protocol and distribute study material among health care professionals. They take care of physicians willing to join the project by providing all the necessary information and assistance. They build national databases and play an active role in checking CRFs sent by Local centres before forwarding them to the Central Registry in Milan.
National coordinators also contribute to coordinate activities with the CPC.